Life Rejuvenation  is the process of maintaining biologically metabolic normality, leading to aging resistance and disease prevention. The foundation of rejuvenation is the structural and functional integrity of the vascular system, particularly the full capacity of microcirculation.

The functionality of microcirculation is essentially regulated by mesenchymal stromal cells (MSCs), or virtually pericytes, which are localized on the surface of vascular endothelial cells. These cells function in maintaining the integrity of capillary endothelial cells, regulating the permeability of capillary endothelium, and importantly, responding to microenvironmental alterations by releasing cytokines or chemokines that activate the tissue rejuvenation potential. 

Under conditions of various ischemia due to capillary vasculature injury, MSCs are lost along with the disappearance of capillary vasculature. Angiogenesis resulting from regeneration of vascular endothelial cells under hypoxic conditions would take place, but the lack of MSCs makes an immature and unstable capillary networks. Replenishing MSCs for reconstruction of the damaged capillary capacity is the most advanced innovation in life rejuvenation.

The TILR team focuses on how to prepare medicinally active MSCs, how to deliver MSCs at the right time efficiently targeting allogeneic MSCs to the needed tissues, and how to ensure the reactivation of life rejuvenation.